Friedrich Nietzsche, The Gay Science.  Die fröhliche Wissenschaft.

First published in 1882.

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The Theory of Poisons.

So many things have to be united in order that scientific thinking may arise, and all the necessary powers must have been devised, exercised, and fostered singly!  In their isolation, however, they have very often had quite a different effect than at present, when they are confined within the limits of scientific thinking and kept mutually in check: they have operated as poisons; for example, the doubting impulse, the denying impulse, the waiting impulse, the collecting impulse, the disintegrating impulse.  Many hecatombs of men were sacrificed ere these impulses learned to understand their juxtaposition and regard themselves as functions of one organising force in one man!  And how far are we still from the point at which the artistic powers and the practical wisdom of life shall co-operate with scientific thinking, so that a higher organic system may be formed, in relation to which the scholar, the physician, the artist, and the lawgiver, as we know them at present, will seem sorry antiquities!  

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